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The main difference between the two substances is in bioavailability.

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30: Diagnostic Criteria for Alcohol Abuse and Dependence. There is limited information concerning the efficacy of atovaquone against other parasitic infections. For toxoplasmosis, most clinical experience with atovaquone has been with intagra 25mg HIV-infected or AIDS patients. gondii is usually a reactivation infection of the central nervous system CNS in persons who have advanced immunosuppression. CNS toxoplasmosis still affects 7% of AIDS patients.

Although pyrimethamine plus sulfadiazine or clindamycin are the drugs of choice for therapy and secondary prophylaxis of toxoplasmosis,,,,, some patients are intolerant of one of these regimens and require alternative therapies.