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Chronic kidney disease is defined as either kidney damage or glomerular filtration rate GFR - the measurement of the kidneys function 60 mL/min/1.73 m for /3 months according to the Kidney Disease Outcomes Quality Initiative Guidelines.

High LDL cholesterol is usually first treated with exercise, weight loss in obese individuals, and a diet low in cholesterol and saturated fats.

When these measures fail, cholesterol-lowering medications such as mevacor can be added. The National Cholesterol Education Program NCEP has published treatment guidelines for use of these medications.

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